I have been on this forum for a long, long time and don't remember anyone ever complaining of sore throat, etc due to adderall....but, that might also be because they had more serious complaints (to them). And I do think it is very possible that acid reflux is the culprit. Try treating that (pepcid) and see what happens. Wondering if you have come under more stress lately...which can contribute to or cause acid reflux. You also might experiment with a stronger Vyvanse dose. You can go higher then the recommended dose. Hope this helps.