Need advice, could this be sinister? Thanks in advance

[angelbox]

I have had breast cancer Er+ and Her2+. and just finished my herceptin and am still on Tamoxifen. I am not BRCA +.I recently had a lot of abdominal crampy pain, bloating, constipation, diarrhoea. I had a CT scan which indicated Ovarian Cyst of 5cm. I then had sever abdo pain, constipation, diarrhoea and vomiting. Redflagged to Gynae who checked tumour markers and done MRI pelvis. MRI has indicated that the cyst has bled and is now smaller so it should settle...fingers crossed!! However tumour markers CA125 and CEA are normal but CA19.9 is elevated at 53 and now 59. I have read some literature on CA19.9 and mucinous ovarian tumours and my consultant said that if bloods continue to be abnormal that they will need to do a laparoscopy to determine if it is mucinous. What could be causing this elevation.  After having already been diagnosed with Breast cancer at 35 im sure you can appreciate my concern.

Many thanks

[angelbox]

Thank you for replying, yes it was thought to be complex. That's why they did an MRI and that has shown that that there has been a bleed. Fingers crossed it is nothing to worry about and that the marker is raised because of an inflammatory response. I am having another scan this month and a laparoscopy and im sure they will check my bloods again. So I will definitely be persistent and keep on top of it.. Thanks again

[hopeshell]

Is the cyst complex?  If it is, I would not wait and ask for a referral to a gynecologic oncologist.   If not, I still would want to have very close follow-up (like weekly) and if it isn't going away completely then I would get it out.  The blood tests for tumor markers are not reliable.  A CA-125 can be a good tool for tracking recurrence in women who had an elevated number prior to dx.  But, many women who have ovca have normal blood tests.  The majority of cysts do turn out to be benign.  But, given your medical history, I think you are being wise to stay on top of it.  I hope all turns out benign!