I have a prior history of C-Diff and numerous ER visits with vomiting, diarhea, rectal bleeding (not dark), abdominal pain and WBC of 22,000. I have some confusion as to whether the elevated WBC count can be from anything other than an infection, or virus. Doctors have told me that vomiting and pain can elevate WBC. Is that true, and if so, to 22,000? My primary care physician told me that vomiting and pain would not drive a WBC up to 22,000. I have these episodes often and the c-diff tests have come back negative on several occasions even though the WBC was still in the 20,000 range. I have also tested positive for the C-Diff toxin on 3 separate occasions. I have completed courses of Vanco and Flagyl. I also have a bowel motility disorder probably secondary to VATER Associated birth defects (spine and imperforate anus). I know this is off topic for this forum and apologize in advance. However, I do have asthma, COPD, and some lung scarring. I am desperate for an answer b/c I haven't gotten good info from the docs (there are tons of them) and I was very impressed by the responses I have seen in this forum. My theory is that I am suffering tertiary effects of bacterial overgrowth due to a motility disorder which results from the imperforate anus and pull thru at birth.